One currently identified example
The inspected US Polident page identifies Poligrip Zinc-Free Denture Adhesive Cream. That is an example of a product claim, not a ranking or a guarantee about every regional Poligrip or competing formula. Confirm the ingredient statement on the package you are buying. [1]
The FDA concern is especially about chronic overuse
FDA describes reports linking excessive use of zinc-containing adhesives with neurological problems. It also says those reports do not establish injury rates or prove harm from use according to the label. Avoid turning a safety concern about overuse into a claim that every correctly used zinc-containing adhesive is harmful. [2]
More adhesive is not the answer to poor fit
Imagine needing increasing amounts to keep dentures stable. Seek a dental fit assessment rather than continually applying more. Follow the product’s quantity instructions, and discuss unexplained numbness or tingling and the adhesive history with a clinician. [2]
| Observation | What it establishes |
|---|---|
| Zinc-free wording | Verify the exact current product |
| Increasing adhesive use | Check denture fit |
| Neurological symptoms | Discuss the exposure history |

Sources for this article
- Poligrip Zinc-Free Denture Adhesive Cream | Polident
Source consulted: 2026-09-20. This is a reference resource, not a claim that we conducted the studies or tested a product. - Denture Adhesives | FDA
Source consulted: 2026-09-20. This is a reference resource, not a claim that we conducted the studies or tested a product.