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    Ingredient guide · Ingredient reference

    GAS6 is a vitamin K dependent signaling protein, not a vitamin K outcome claim

    GAS6 stands for growth arrest-specific protein 6. Its vitamin K dependent modification helps explain protein chemistry, but that mechanism alone does not establish a benefit from taking extra vitamin K.

    Read the evidence ↓

    Supplement Science Insights Editorial Team

    Published September 23, 2026

    GAS6 acts as a receptor ligand

    The curated human UniProt entry identifies GAS6 as a ligand for AXL, TYRO3 and MER receptor tyrosine kinases. These signaling systems participate in processes including cell survival, adhesion and migration. [1]

    GAS6 is a protein signal. The name does not identify a vitamin formulation or a clinical endpoint. [1]

    Vitamin K dependence concerns a chemical modification

    UniProt describes vitamin K dependent formation of gamma-carboxyglutamate residues, which are needed for calcium binding. This is a post-translational change to the protein. [1]

    A required biochemical process is not a dose-response trial. The entry does not show that raising supplemental vitamin K improves a disease by increasing GAS6 activity. [1]

    Do not turn a pathway diagram into a treatment claim

    Imagine a diagram connects vitamin K to GAS6 modification. That connection explains a mechanism; it does not supply a tested supplement dose or patient benefit.

    Key distinctions — GAS6 is a vitamin K dependent signaling protein, not a vitamin K outcome claim
    DetailInterpretation
    GAS6Signaling protein
    Vitamin K dependenceCarboxylation chemistry
    Extra supplementationBenefit not established by mechanism
    GAS6 is a vitamin K dependent signaling protein, not a vitamin K outcome claim — original article outline diagram
    Original editorial diagram of this article’s sections; no product photograph or clinical finding is depicted.

    Sources for this article

    1. gas6-uniprot
      Source consulted: 2026-09-18. This is a reference resource, not a claim that we conducted the studies or tested a product.