Botanical guide · Ingredient reference

Ginkgo and antidepressant sexual effects: improvement also occurred with placebo

A randomized trial did not find ginkgo superior to placebo for antidepressant-associated sexual dysfunction. Improvement from a person’s starting score was not enough to establish efficacy.

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Supplement Science Insights Editorial Team

Published September 23, 2026

Study and results

Thirty-seven participants received ginkgo or placebo for two months in a double-blind study. Investigators compared outcomes at weeks two, four and eight. [1]

The groups did not differ significantly at those assessments. Both showed improvement in some aspects of sexual function compared with baseline, illustrating why a control group matters. [1]

Interpretation and limitations

The small study cannot settle every sexual-health question or every preparation, but it did not replicate an earlier positive finding. Funding and conflicts were not established from the abstract. The findings do not justify stopping prescribed treatment or assuming that a botanical will reverse its adverse effects. [1]

A hypothetical distinction

Imagine both treatment and placebo groups improve by similar amounts. Reporting only the active group’s change would overstate evidence that the treatment caused improvement.

Evidence summary — Ginkgo and antidepressant sexual effects
DetailInterpretation
Baseline changeNot a treatment comparison
Placebo comparisonNo significant difference
Other preparationsNot established
Ginkgo and antidepressant sexual effects: improvement also occurred with placebo — original article outline diagram
Original editorial diagram of this article’s sections; no product photograph or clinical finding is depicted.

Sources for this article

  1. A placebo-controlled, double-blind trial of Ginkgo biloba for antidepressant-induced sexual dysfunction - PubMed
    Source consulted: 2026-09-19. This is a reference resource, not a claim that we conducted the studies or tested a product.