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Theanine plus caffeine: blood pressure and jitteriness were not interchangeable

A controlled experiment found that theanine modified caffeine’s pressure effect without reliably removing its subjective stimulation.

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Supplement Science Insights Editorial Team

Published September 23, 2026

The study and its comparison

Forty-eight healthy adults received caffeine, theanine, both, or neither. The doses were 250 milligrams of caffeine and 200 milligrams of theanine; testing began around 40 minutes later. [1]

Caffeine increased alertness, jitteriness and blood pressure. Theanine opposed the pressure rise, but did not significantly change jitteriness or alertness. It also slowed overall reaction time on the visual-probe task. [1]

What the finding establishes

This single-session result does not establish that adding theanine makes any caffeinated product safe or improves every form of attention. The fixed doses and task should remain attached to the claim. Funding and conflicts were not established from the retrieved abstract. Subjective calm and cardiovascular measurements are separate outcomes. [1]

A hypothetical distinction

Imagine someone still feels jittery despite a smaller pressure response. The two findings can coexist without contradiction.

Interpretation checklist — Theanine plus caffeine
DetailInterpretation
Measured outcomeKeep the endpoint specific
Study preparationNot every retail product
Remaining uncertaintyNot resolved by a mechanism
Theanine plus caffeine: blood pressure and jitteriness were not interchangeable — original article outline diagram
Original editorial diagram of this article’s sections; no product photograph or clinical finding is depicted.

Sources for this article

  1. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together - PubMed
    Source consulted: 2026-09-19. This is a reference resource, not a claim that we conducted the studies or tested a product.