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Fish oil and acne scars: an active-acne trial did not test scar removal

A small study reported improvement in active acne lesions with oral fatty-acid supplements. It did not establish that fish oil repairs established acne scars or works when applied to the face.

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Supplement Science Insights Editorial Team

Published September 23, 2026

The measured outcomes concerned active acne

Forty-five people with mild-to-moderate acne entered a ten-week randomized trial. Groups received EPA/DHA, a gamma-linolenic-acid preparation or a control condition. [1]

The report described reductions in inflammatory and non-inflammatory lesions in the supplemented groups, with supporting changes in inflammatory tissue findings. Those measurements concern current acne activity. [1]

Lesion counts do not measure established scar remodeling

The study did not demonstrate removal of pitted scars, raised scars or persistent post-acne color changes. It also studied oral supplementation, not direct application of capsule contents to skin. [1]

No severe adverse effects were reported, but the small sample and short follow-up cannot establish universal safety or durable benefit. Funding and conflicts were not established from the abstract. The findings are preliminary and should not be used to promise scar correction or replace a dermatologic assessment of the actual skin concern. [1]

Name what changed on the skin

Imagine fewer new inflamed spots appear during a study. That does not establish that scars left by earlier acne became shallower or disappeared.

Evidence summary — Fish oil and acne scars
DetailInterpretation
Active lesion countStudied outcome
Established scarsNot measured
Topical capsule oilNot tested
Fish oil and acne scars: an active-acne trial did not test scar removal — original article outline diagram
Original editorial diagram of this article’s sections; no product photograph or clinical finding is depicted.

Sources for this article

  1. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial - PubMed
    Source consulted: 2026-09-19. This is a reference resource, not a claim that we conducted the studies or tested a product.