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Fish oil and muscle: an older-adult trial is not a bodybuilding protocol

A six-month study reported improved muscle volume and selected strength measures in healthy older adults. The findings cannot be assumed to produce the same gains in young trained athletes.

Read the evidence ↓

Supplement Science Insights Editorial Team

Published September 23, 2026

The trial studied age-related muscle concerns

Sixty adults aged 60–85 were randomized to fish-oil-derived omega-3 or corn oil for six months. Forty-four completed the study, with similar completion proportions in both groups. [1]

Compared with control, omega-3 treatment increased thigh muscle volume by about 3.6%, handgrip strength by 2.3 kilograms and one-repetition maximum strength by about 4%. The power result was a nonsignificant trend. [1]

The outcomes do not establish every practical benefit

The study did not demonstrate fewer falls, longer independent living or a particular bodybuilding result. A percentage change in thigh muscle volume is not the same as the same percentage gain in total body muscle. [1]

Funding and conflicts were not established from the abstract. The sample size, attrition and population limit transfer to younger athletes or people with major illness. These results do not identify a universal supplement amount or replace resistance exercise and adequate nutrition. [1]

Keep the measured body region attached

Imagine a scan finds a small change in thigh muscle volume. Reporting that as an identical change in whole-body muscle mass would alter the measurement.

Evidence summary — Fish oil and muscle
DetailInterpretation
Ages 60–85Studied population
44 completersAttrition matters
Young bodybuildersNot directly studied
Fish oil and muscle: an older-adult trial is not a bodybuilding protocol — original article outline diagram
Original editorial diagram of this article’s sections; no product photograph or clinical finding is depicted.

Sources for this article

  1. Fish oil-derived n-3 PUFA therapy increases muscle mass and function in healthy older adults - PubMed
    Source consulted: 2026-09-19. This is a reference resource, not a claim that we conducted the studies or tested a product.