The library

Healthy aging

Read joint-health and other aging-related evidence with attention to the preparation, population and outcome.

257 articles · Page 1 of 11

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  1. Page 1Is Alaya collagen good? Ingredients, evidence and limitationsthrough Citicoline memory trial: secondary benefits need their endpoint labels
  2. Page 2Citicoline after acute stroke: ICTUS found no recovery benefitthrough What is collagen induction therapy? Microneedling benefits and limits
  3. Page 3Where collagen is found in the skinthrough Collagen or glucosamine for arthritis? No universal winner
  4. Page 4Collagen for weight loss: body-composition findings are not a guaranteed fat-burning effectthrough Creatine in Parkinson’s disease: a large trial stopped for futility
  5. Page 5Dentin is mineralized tissue with a collagen-containing matrixthrough Does glutathione lower cholesterol?
  6. Page 6Glutathione during pregnancy: biology is not a supplement recommendationthrough Lipoic acid in progressive MS: walking benefit was not demonstrated
  7. Page 7Liquid collagen versus pills: format alone does not establish better resultsthrough NAC for hair pulling: adult and pediatric trials disagreed
  8. Page 8NAD supplements: forms, dosing and evidence limitsthrough Quercetin in rheumatoid arthritis: symptoms and joint counts differed
  9. Page 9Does quercetin help with weight loss?through Type II collagen for joints: form, benefits and safety
  10. Page 10UC-II knee trial: symptom improvement does not establish cartilage regrowththrough Can vitamin C enter through skin? Delivery depends on the formulation
  11. Page 11Vitamin C is not the same as an exfoliating acidthrough Zinc-carnosine and aspirin-related small-bowel injury: a pilot study
Ingredient guide

Is Alaya collagen good? Ingredients, evidence and limitations

Alaya Multi Collagen combines several collagen sources with MSM, glucosamine and chondroitin. That broader formula is not automatically more effective than a simpler product. Whether it fits depends on the exact variant, allergies, medicines and the outcome you want.

3 sources
Ingredient guide

Can you take astaxanthin and zeaxanthin together?

Whether an astaxanthin and zeaxanthin combination is appropriate depends on the product, amounts, health conditions and other treatment. Their shared carotenoid category does not establish extra benefit or universal safety when combined. In particular, adding astaxanthin should not be confused with following the studied AREDS2 formula.

2 sources
Ingredient guide

B vitamins and memory: assess deficiency without promising a brain boost

Vitamin B12 deficiency can cause cognitive difficulties, but routine B-vitamin supplementation is not an established memory enhancer for everyone. A nutrient association and successful treatment of deficiency do not prove that extra vitamins prevent dementia in a person with adequate intake.

4 sources
Ingredient guide

What is the best probiotic for menopause symptoms?

No probiotic is established as the universally best treatment for menopause symptoms. Reviews report some promising findings, but studies differ in strains, routes and accompanying treatments and often have substantial risk of bias. Hot flashes, vaginal symptoms, bowel concerns and bone health should be assessed as separate outcomes.

4 sources
Ingredient guide

Supplements for bones and joints: what actually helps?

Bone strength and joint pain are related concerns but not the same treatment target. Adequate calcium, vitamin D and protein support bone health. A supplement that fills a dietary gap does not automatically relieve osteoarthritis or replace osteoporosis medicines when fracture risk warrants them.

3 sources
Ingredient guide

Bovine types I and III collagen: source, processing and tissue roles

Bovine collagen comes from cattle-derived connective tissue. Types I and III describe structural proteins in the source, while processing determines what a supplement contains. Those names explain identity; they do not guarantee that a swallowed product rebuilds a particular body part.

3 sources
Ingredient guide

Brittle nails: deficiency is one possibility, not a diagnosis

Nails can become brittle with age, repeated water or cleaning exposure, injury and several medical conditions. A nail that splits does not identify a specific vitamin shortage or prove that a beauty supplement will help.

2 sources
Ingredient guide

Do ceramide supplements work? Evidence for skin hydration

Oral ceramides have some evidence for improving skin hydration and reducing water loss. The studies are relatively small, use varied formulations and do not establish that every ceramide product treats eczema or reverses aging.

2 sources
Ingredient guide

Do chemical peels stimulate collagen production?

Some professionally selected chemical peels stimulate skin remodeling, including collagen and elastin production. Their effects depend on the peel and the condition being treated. A strong home peel is not a safe shortcut to more collagen.

2 sources